cat ~/.fonts.conf
<?xml version="1.0"?>
<!DOCTYPE fontconfig SYSTEM "fonts.dtd">
<fontconfig>
<match target="font" >
<edit mode="assign" name="hinting" >
<bool>true</bool>
</edit>
</match>
<match target="font" >
<edit mode="assign" name="hintstyle" >
<const>hintmedium</const>
</edit>
</match>
<match target="font" >
<edit mode="assign" name="rgba" >
<const>rgb</const>
</edit>
</match>
<match target="font" >
<edit mode="assign" name="antialias" >
<bool>true</bool>
</edit>
</match>
<match target="pattern">
<test qual="any" name="family">
<string>Times</string>
</test>
<edit name="family" mode="assign">
<string>Times New Roman</string>
</edit>
</match>
<match target="pattern" >
<test name="family" qual="any" >
<string>Helvetica</string>
</test>
<edit mode="assign" name="family" >
<string>Arial</string>
</edit>
</match>
</fontconfig>
eselect fontconfig list
Available fontconfig .conf files (* is enabled):
[1] 10-autohint.conf
[2] 10-no-sub-pixel.conf
[3] 10-sub-pixel-bgr.conf
[4] 10-sub-pixel-rgb.conf *
[5] 10-sub-pixel-vbgr.conf
[6] 10-sub-pixel-vrgb.conf
[7] 10-unhinted.conf
[8] 20-fix-globaladvance.conf *
[9] 20-unhint-small-dejavu-sans.conf
[10] 20-unhint-small-dejavu-sans-mono.conf
[11] 20-unhint-small-dejavu-serif.conf
[12] 20-unhint-small-vera.conf *
[13] 25-unhint-nonlatin.conf
[14] 30-metric-aliases.conf
[15] 30-urw-aliases.conf
[16] 40-nonlatin.conf *
[17] 45-latin.conf *
[18] 49-sansserif.conf *
[19] 50-user.conf *
[20] 51-local.conf *
[21] 57-dejavu-sans.conf
[22] 57-dejavu-sans-mono.conf
[23] 57-dejavu-serif.conf
[24] 60-latin.conf *
[25] 60-liberation.conf *
[26] 65-culmus.conf
[27] 65-fonts-persian.conf *
[28] 65-khmer.conf
[29] 65-nonlatin.conf *
[30] 69-unifont.conf *
[31] 70-no-bitmaps.conf
[32] 70-yes-bitmaps.conf
[33] 80-delicious.conf *
[34] 90-synthetic.conf *
Не претендую на абсолютную идеальность настроек, но меня всё устраивает ;-)